Our achievements

Paris FLOW Tech has conducted numerous collaborations with its industrial partners

Some representative examples

Benzyl monochlorination: synthesis of an intermediate for the pharmaceutical industry

  • Key reaction
    Photochemical halogenation
  • Industrial / academic research
    Research collaboration with an industrial partner
  • Objective(s)
    • Achieve selectivity to desired product > 90%.
    • Pilot scale transposition
  • Reactor used / Results
    • Industrial continuous photochemical reactor (Corning® AFRTM PHOTO G1-LF)
    • Selectivity towards desired product of 95%
    • Production of 55g of product over 4 hours.

Photooxygenation of a biosourced molecule

  • Key reaction
    Photosensitised reaction
  • Industrial / academic research
    Academic research
  • Objective(s)
    Kinetic study
  • Reactor used / Results
    • Industrial Photochemical Continuous Reactor (AFRTM PHOTO G1-LF from Corning®)
    • Kinetic law

Synthesis of an amino acid, an ingredient for cosmetics

  • Key reaction
    Electrophilic reaction
  • Industrial / academic research
    Research collaboration with an industrial partner
  • Objective(s)
    • Multi-step synthesis: achieving all steps in continuous flow and in sequence
  • Reactor used / Results
    • Proof of concept
    • Industrial continuous flow reactor (AFRTM G1-LF from Corning®)
    • 6.8 g produced in 1 hour

Oxidation of cyclic amines

  • Key reaction
    Oxygen plasma oxidation
  • Industrial / academic research
    Research collaboration with an industrial partner
  • Objective (s)
    Feasibility study
  • Reactor used / Results
    • Continuous flow microreactor
    • New process without catalyst

Reductive alkylation of methanol with aldehydes: synthesis of methyl ethers

  • Key reaction
    Catalytic fixed bed hydrogenation with gas/liquid two-phase flow
  • Industrial / academic research
    Academic research
  • Objective (s)
    • Use of an inexpensive catalyst
    • Increase process safety
  • Reactor used / Results
    • Proof of concept
    • Industrial continuous reactor (H-Cube Pro Thales Nano®)
    • Pd/C catalyst and atmospheric pressure
    • Screening of 10 aldehydes
    • Conversion > 99% and selectivity ranging from 70 to 99%

Production of methanol from CO2

  • Key reaction
    Catalytic hydrogenation in a fixed bed under high pressure and high temperature
  • Industrial / academic research
    Research collaboration with an industry partner
  • Objective (s)
    Feasibility study
  • Reactor used / Results
    • Industrial continuous reactor (Phoenix Thales Nano®)
    • Catalyst: ZnO/CuO/Al2O3
    • Scaled up for production on the order of L/min